STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
GAK48318.1Short chain dehydrogenase family protein; 3-ketoacyl-(acyl-carrier-protein) reductase; Validated; PRK05653; NAD(P) binding site [chemical binding]; Short-chain alcohol dehydrogenase of unknown specificity [Pediococcus pentosaceus ATCC 25745]; classical (c) SDRs; cd05233; gene_1416; identified by MetaGeneAnnotator; putative; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (249 aa)    
Predicted Functional Partners:
dltA
D-alanine-poly(phosphoribitol) ligase subunit 1; Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D- alanyl carrier protein (Dcp) DltC. In an ATP-dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall. Belongs to t [...]
 
  
 0.908
GAK48319.1
Acetyltransferase (isoleucine patch superfamily) [General function prediction only]; COG0110; Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes..; cl00160; galactoside O-acetyltransferase [Pediococcus acidilactici 7_4]; gene_1417; identified by MetaGeneAnnotator; putative; putative CoA binding site [chemical binding]; putative trimer interface [polypeptide binding].
     
 0.785
GAK48317.1
2,5-diketo-D-gluconic acid reductase; Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial..; cd06660; Aldo/keto reductase family; pfam00248; aldo/keto reductase [Pediococcus pentosaceus ATCC 25745]; catalytic tetrad [active]; gene_1415; identified by MetaGeneAnnotator; putative.
     
 0.779
GAK48320.1
Bacterial regulatory helix-turn-helix protein, lysR family; pfam00126; The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; cd05466; Transcriptional regulator [Transcription]; COG0583; dimerization interface [polypeptide binding]; fhu operon transcription regulator [Pediococcus acidilactici 7_4]; gene_1418; identified by MetaGeneAnnotator; putative.
 
     0.612
GAK47572.1
Short-chain dehydrogenase; KEGG: rme:Rmet_4288 9.1e-48 short chain dehydrogenase; Psort location: Cytoplasmic, score: 9.97; NAD(P) binding site [chemical binding]; Rossmann-fold NAD(P)(+)-binding proteins; cl09931; gene_670; identified by MetaGeneAnnotator; putative; short chain dehydrogenase domain protein, partial [Corynebacterium durum F0235]; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
 
  
 
0.588
GAK47826.1
4-aminobutyrate aminotransferase [Lactobacillus vaginalis ATCC 49540]; 4-aminobutyrate aminotransferase; Provisional; Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; cd00610; COG: COG0160; catalytic residue [active]; gene_924; identified by MetaGeneAnnotator; putative; inhibitor-cofactor binding pocket; pyridoxal 5'-phosphate binding site [chemical binding].
    
  0.479
GAK48771.1
Hypothetical protein; Gene_1869; identified by MetaGeneAnnotator; putative.
    
 0.479
GAK48649.1
Bifunctional acetaldehyde-CoA/alcohol dehydrogenase; C-terminal alcohol dehydrogenase domain of the acetaldehyde dehydrogenase-alcohol dehydrogenase bifunctional two-domain protein (AAD); cd08178; Coenzyme A acylating aldehyde dehydrogenase (ACDH), ALDH family 20-like; cd07122; bifunctional acetaldehyde-CoA/alcohol dehydrogenase [Lactobacillus brevis ATCC 367]; bifunctional acetaldehyde-CoA/alcohol dehydrogenase; Provisional; gene_1747; identified by MetaGeneAnnotator; putative; metal binding site [ion binding]; putative active site [active]; putative catalytic cysteine [active].
  
  
 0.454
gmK
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
      0.450
GAK48443.1
Nitroreductase; COG: COG0778; Pfam: PF00881; InterPro: IPR000415; FMN binding site [chemical binding]; NADPH bind site [chemical binding]; This family contains NADPH-dependent flavin reductase and oxygen-insensitive nitroreductase. These enzymes are homodimeric flavoproteins that contain one FMN per monomer as a cofactor. Flavin reductase catalyzes the reduction of flavin by using NADPH as..; cd02146; dimer interface [polypeptide binding]; flavin reductase [Lactobacillus hilgardii ATCC 8290]; gene_1541; identified by MetaGeneAnnotator; putative; Belongs to the flavin oxidoreductase frp [...]
  
 
 0.419
Your Current Organism:
Lactobacillus oryzae
NCBI taxonomy Id: 1291743
Other names: L. oryzae JCM 18671, Lactobacillus oryzae JCM 18671, Lactobacillus oryzae SG293, Lactobacillus sp. JCM 18671, Lactobacillus sp. SG293
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