STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
dltAD-alanine-poly(phosphoribitol) ligase subunit 1; Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D- alanyl carrier protein (Dcp) DltC. In an ATP-dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall. Belongs to t [...] (501 aa)    
Predicted Functional Partners:
dltC
D-alanine-poly(phosphoribitol) ligase subunit 2; Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC- carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall.
 
 0.999
dtlB
D-alanine transfer protein DltB; Could be involved in the transport of activated D-alanine through the membrane.
  
 0.999
dltD
D-alanyl transfer protein DltD; Gene_1629; identified by MetaGeneAnnotator; putative.
 
  
 0.993
ddl
D-alanine-D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family.
   
 
 0.965
GAK47352.1
Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.
    
 0.958
acpP
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
  
 0.947
GAK48537.1
Putative penicillin-binding protein; Beta-lactamase class C; gene_1635; identified by MetaGeneAnnotator; putative.
 
  
 0.930
GAK48259.1
Short-chain dehydrogenase/reductase SDR; NAD(P) binding site [chemical binding]; Rossmann-fold NAD(P)(+)-binding proteins; cl09931; Short-chain alcohol dehydrogenase of unknown specificity [General function prediction only]; gene_1357; identified by MetaGeneAnnotator; putative; identified by match to protein family HMM PF00106; match to protein family HMM PF08659; short-chain dehydrogenase/reductase SDR [Listeria seeligeri FSL N1- 067]; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
 
 0.928
GAK48318.1
Short chain dehydrogenase family protein; 3-ketoacyl-(acyl-carrier-protein) reductase; Validated; PRK05653; NAD(P) binding site [chemical binding]; Short-chain alcohol dehydrogenase of unknown specificity [Pediococcus pentosaceus ATCC 25745]; classical (c) SDRs; cd05233; gene_1416; identified by MetaGeneAnnotator; putative; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
 
  
 0.908
GAK47860.1
Monooxygenase protein; COG: COG2141; Pfam: PF00296; InterPro: IPR011251; Flavin-utilizing monoxygenases; cl07892; gene_958; identified by MetaGeneAnnotator; putative; possible oxidoreductase [Lactobacillus paracasei subsp. paracasei ATCC 25302].
  
 0.810
Your Current Organism:
Lactobacillus oryzae
NCBI taxonomy Id: 1291743
Other names: L. oryzae JCM 18671, Lactobacillus oryzae JCM 18671, Lactobacillus oryzae SG293, Lactobacillus sp. JCM 18671, Lactobacillus sp. SG293
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