node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
GAK46972.1 | GAK48598.1 | LOSG293_010710 | LOSG293_400140 | RNA 2'-O ribose methyltransferase substrate binding; smart00967; SpoU rRNA Methylase family; pfam00588; gene_70; identified by MetaGeneAnnotator; putative; rRNA methylase [Lactobacillus plantarum JDM1]; rRNA methylases [Translation, ribosomal structure and biogenesis]; COG0566; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | Pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | 0.820 |
GAK46972.1 | rplC | LOSG293_010710 | LOSG293_180280 | RNA 2'-O ribose methyltransferase substrate binding; smart00967; SpoU rRNA Methylase family; pfam00588; gene_70; identified by MetaGeneAnnotator; putative; rRNA methylase [Lactobacillus plantarum JDM1]; rRNA methylases [Translation, ribosomal structure and biogenesis]; COG0566; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. | 0.814 |
GAK46972.1 | rplK | LOSG293_010710 | LOSG293_200040 | RNA 2'-O ribose methyltransferase substrate binding; smart00967; SpoU rRNA Methylase family; pfam00588; gene_70; identified by MetaGeneAnnotator; putative; rRNA methylase [Lactobacillus plantarum JDM1]; rRNA methylases [Translation, ribosomal structure and biogenesis]; COG0566; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | 50S ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. | 0.810 |
GAK46972.1 | rplM | LOSG293_010710 | LOSG293_290170 | RNA 2'-O ribose methyltransferase substrate binding; smart00967; SpoU rRNA Methylase family; pfam00588; gene_70; identified by MetaGeneAnnotator; putative; rRNA methylase [Lactobacillus plantarum JDM1]; rRNA methylases [Translation, ribosomal structure and biogenesis]; COG0566; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | 50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.813 |
GAK46972.1 | rplO | LOSG293_010710 | LOSG293_180090 | RNA 2'-O ribose methyltransferase substrate binding; smart00967; SpoU rRNA Methylase family; pfam00588; gene_70; identified by MetaGeneAnnotator; putative; rRNA methylase [Lactobacillus plantarum JDM1]; rRNA methylases [Translation, ribosomal structure and biogenesis]; COG0566; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | 50S ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. | 0.805 |
GAK46972.1 | rplQ | LOSG293_010710 | LOSG293_180010 | RNA 2'-O ribose methyltransferase substrate binding; smart00967; SpoU rRNA Methylase family; pfam00588; gene_70; identified by MetaGeneAnnotator; putative; rRNA methylase [Lactobacillus plantarum JDM1]; rRNA methylases [Translation, ribosomal structure and biogenesis]; COG0566; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | 50S ribosomal protein L17 [Lactobacillus rhamnosus GG]; 50S ribosomal protein L17; Validated; PRK05591; gene_1145; identified by MetaGeneAnnotator; putative; strain coidentity: ATCC 53103 = GG; synonym: Lactobacillus rhamnosus ATCC 53103. | 0.807 |
GAK46972.1 | rplU | LOSG293_010710 | LOSG293_010440 | RNA 2'-O ribose methyltransferase substrate binding; smart00967; SpoU rRNA Methylase family; pfam00588; gene_70; identified by MetaGeneAnnotator; putative; rRNA methylase [Lactobacillus plantarum JDM1]; rRNA methylases [Translation, ribosomal structure and biogenesis]; COG0566; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | 50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. | 0.809 |
GAK46972.1 | rsfS | LOSG293_010710 | LOSG293_010860 | RNA 2'-O ribose methyltransferase substrate binding; smart00967; SpoU rRNA Methylase family; pfam00588; gene_70; identified by MetaGeneAnnotator; putative; rRNA methylase [Lactobacillus plantarum JDM1]; rRNA methylases [Translation, ribosomal structure and biogenesis]; COG0566; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | Iojap family protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.815 |
GAK46972.1 | trmE | LOSG293_010710 | LOSG293_070330 | RNA 2'-O ribose methyltransferase substrate binding; smart00967; SpoU rRNA Methylase family; pfam00588; gene_70; identified by MetaGeneAnnotator; putative; rRNA methylase [Lactobacillus plantarum JDM1]; rRNA methylases [Translation, ribosomal structure and biogenesis]; COG0566; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | GTPase and tRNA-U34 5-formylation enzyme TrmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | 0.816 |
GAK48145.1 | GAK48598.1 | LOSG293_200100 | LOSG293_400140 | rRNA methyltransferase; COG: COG0566; RNA 2'-O ribose methyltransferase substrate binding; pfam08032; SpoU rRNA Methylase family; pfam00588; TrmH family tRNA/rRNA methyltransferase [Lactobacillus vaginalis ATCC 49540]; gene_1243; identified by MetaGeneAnnotator; putative; rRNA methylase, putative, group 3; TIGR00186; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | Pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | 0.848 |
GAK48145.1 | rplC | LOSG293_200100 | LOSG293_180280 | rRNA methyltransferase; COG: COG0566; RNA 2'-O ribose methyltransferase substrate binding; pfam08032; SpoU rRNA Methylase family; pfam00588; TrmH family tRNA/rRNA methyltransferase [Lactobacillus vaginalis ATCC 49540]; gene_1243; identified by MetaGeneAnnotator; putative; rRNA methylase, putative, group 3; TIGR00186; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. | 0.814 |
GAK48145.1 | rplK | LOSG293_200100 | LOSG293_200040 | rRNA methyltransferase; COG: COG0566; RNA 2'-O ribose methyltransferase substrate binding; pfam08032; SpoU rRNA Methylase family; pfam00588; TrmH family tRNA/rRNA methyltransferase [Lactobacillus vaginalis ATCC 49540]; gene_1243; identified by MetaGeneAnnotator; putative; rRNA methylase, putative, group 3; TIGR00186; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | 50S ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. | 0.932 |
GAK48145.1 | rplM | LOSG293_200100 | LOSG293_290170 | rRNA methyltransferase; COG: COG0566; RNA 2'-O ribose methyltransferase substrate binding; pfam08032; SpoU rRNA Methylase family; pfam00588; TrmH family tRNA/rRNA methyltransferase [Lactobacillus vaginalis ATCC 49540]; gene_1243; identified by MetaGeneAnnotator; putative; rRNA methylase, putative, group 3; TIGR00186; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | 50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.818 |
GAK48145.1 | rplO | LOSG293_200100 | LOSG293_180090 | rRNA methyltransferase; COG: COG0566; RNA 2'-O ribose methyltransferase substrate binding; pfam08032; SpoU rRNA Methylase family; pfam00588; TrmH family tRNA/rRNA methyltransferase [Lactobacillus vaginalis ATCC 49540]; gene_1243; identified by MetaGeneAnnotator; putative; rRNA methylase, putative, group 3; TIGR00186; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | 50S ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. | 0.805 |
GAK48145.1 | rplQ | LOSG293_200100 | LOSG293_180010 | rRNA methyltransferase; COG: COG0566; RNA 2'-O ribose methyltransferase substrate binding; pfam08032; SpoU rRNA Methylase family; pfam00588; TrmH family tRNA/rRNA methyltransferase [Lactobacillus vaginalis ATCC 49540]; gene_1243; identified by MetaGeneAnnotator; putative; rRNA methylase, putative, group 3; TIGR00186; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | 50S ribosomal protein L17 [Lactobacillus rhamnosus GG]; 50S ribosomal protein L17; Validated; PRK05591; gene_1145; identified by MetaGeneAnnotator; putative; strain coidentity: ATCC 53103 = GG; synonym: Lactobacillus rhamnosus ATCC 53103. | 0.807 |
GAK48145.1 | rplU | LOSG293_200100 | LOSG293_010440 | rRNA methyltransferase; COG: COG0566; RNA 2'-O ribose methyltransferase substrate binding; pfam08032; SpoU rRNA Methylase family; pfam00588; TrmH family tRNA/rRNA methyltransferase [Lactobacillus vaginalis ATCC 49540]; gene_1243; identified by MetaGeneAnnotator; putative; rRNA methylase, putative, group 3; TIGR00186; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | 50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. | 0.809 |
GAK48145.1 | rsfS | LOSG293_200100 | LOSG293_010860 | rRNA methyltransferase; COG: COG0566; RNA 2'-O ribose methyltransferase substrate binding; pfam08032; SpoU rRNA Methylase family; pfam00588; TrmH family tRNA/rRNA methyltransferase [Lactobacillus vaginalis ATCC 49540]; gene_1243; identified by MetaGeneAnnotator; putative; rRNA methylase, putative, group 3; TIGR00186; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | Iojap family protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.807 |
GAK48145.1 | trmE | LOSG293_200100 | LOSG293_070330 | rRNA methyltransferase; COG: COG0566; RNA 2'-O ribose methyltransferase substrate binding; pfam08032; SpoU rRNA Methylase family; pfam00588; TrmH family tRNA/rRNA methyltransferase [Lactobacillus vaginalis ATCC 49540]; gene_1243; identified by MetaGeneAnnotator; putative; rRNA methylase, putative, group 3; TIGR00186; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | GTPase and tRNA-U34 5-formylation enzyme TrmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | 0.816 |
GAK48598.1 | GAK46972.1 | LOSG293_400140 | LOSG293_010710 | Pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | RNA 2'-O ribose methyltransferase substrate binding; smart00967; SpoU rRNA Methylase family; pfam00588; gene_70; identified by MetaGeneAnnotator; putative; rRNA methylase [Lactobacillus plantarum JDM1]; rRNA methylases [Translation, ribosomal structure and biogenesis]; COG0566; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | 0.820 |
GAK48598.1 | GAK48145.1 | LOSG293_400140 | LOSG293_200100 | Pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | rRNA methyltransferase; COG: COG0566; RNA 2'-O ribose methyltransferase substrate binding; pfam08032; SpoU rRNA Methylase family; pfam00588; TrmH family tRNA/rRNA methyltransferase [Lactobacillus vaginalis ATCC 49540]; gene_1243; identified by MetaGeneAnnotator; putative; rRNA methylase, putative, group 3; TIGR00186; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | 0.848 |