STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GAK48598.1Pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. (297 aa)    
Predicted Functional Partners:
GAK48145.1
rRNA methyltransferase; COG: COG0566; RNA 2'-O ribose methyltransferase substrate binding; pfam08032; SpoU rRNA Methylase family; pfam00588; TrmH family tRNA/rRNA methyltransferase [Lactobacillus vaginalis ATCC 49540]; gene_1243; identified by MetaGeneAnnotator; putative; rRNA methylase, putative, group 3; TIGR00186; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
 
 
 0.848
rplC
50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.
 
 
   0.827
GAK46972.1
RNA 2'-O ribose methyltransferase substrate binding; smart00967; SpoU rRNA Methylase family; pfam00588; gene_70; identified by MetaGeneAnnotator; putative; rRNA methylase [Lactobacillus plantarum JDM1]; rRNA methylases [Translation, ribosomal structure and biogenesis]; COG0566; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
 
 
 0.820
rsfS
Iojap family protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
  
 
 0.805
rplU
50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.
   
   0.804
trmE
GTPase and tRNA-U34 5-formylation enzyme TrmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
   
 
 0.801
rplQ
50S ribosomal protein L17 [Lactobacillus rhamnosus GG]; 50S ribosomal protein L17; Validated; PRK05591; gene_1145; identified by MetaGeneAnnotator; putative; strain coidentity: ATCC 53103 = GG; synonym: Lactobacillus rhamnosus ATCC 53103.
   
   0.799
rplM
50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.
  
   0.795
rplO
50S ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.
  
   0.794
rplK
50S ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
   
   0.792
Your Current Organism:
Lactobacillus oryzae
NCBI taxonomy Id: 1291743
Other names: L. oryzae JCM 18671, Lactobacillus oryzae JCM 18671, Lactobacillus oryzae SG293, Lactobacillus sp. JCM 18671, Lactobacillus sp. SG293
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