STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hxlB6-phospho-3-hexuloisomerase; 3-hexulose-6-phosphate isomerase [Lactobacillus buchneri ATCC 11577]; COG: COG0794; Pfam: PF01380; InterPro: IPR001347; Hexulose-6-phosphate isomerase (PHI). PHI is a member of the SIS (Sugar ISomerase domain) superfamily. In the ribulose monophosphate pathway of formaldehyde fixation, hexulose-6-phosphate synthase catalyzes the condensation of ribulose-5-phosphate with..; cd05005; Predicted sugar phosphate isomerase involved in capsule formation [Cell envelope biogenesis, outer membrane]; COG0794; gene_1706; identified by MetaGeneAnnotator; putative; tetra [...] (180 aa)    
Predicted Functional Partners:
hxlA
3-hexulose-6-phosphate synthase; 3-Keto-L-gulonate 6-phosphate decarboxylase (KGPDC) and D-arabino-3-hexulose-6-phosphate synthase (HPS). KGPDC catalyzes the formation of L-xylulose 5-phosphate and carbon dioxide from 3-keto-L-gulonate 6-phosphate as part of the anaerobic pathway for..; cd04726; KEGG: lbr:LVIS_0442 1.0e-64 3-hexulose-6-phosphate synthase related protein; K08093 3-hexulose-6-phosphate synthase; Psort location: Cytoplasmic, score: 8.96; dimer interface [polypeptide binding]; gene_1707; identified by MetaGeneAnnotator; putative; magnesium binding site [ion binding]; oroti [...]
 
 0.999
pgi
KEGG: lbr:LVIS_1312 9.0e-199 glucose-6-phosphate isomerase; K01810 glucose-6-phosphate isomerase; Psort location: Cytoplasmic, score: 9.26; Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the first SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of..; cd05015; Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the second SIS domain. PGI is a multifunctional enzyme which as [...]
    
 0.976
eda
2-dehydro-3-deoxyphosphogluconate aldolase [Lactobacillus buchneri CD034]; 2-keto-3-deoxy-6-phosphogluconate aldolase [Carbohydrate transport and metabolism]; COG0800; KDPG and KHG aldolase; cd00452; catalytic residue [active]; gene_1705; identified by MetaGeneAnnotator; putative; intersubunit interface [polypeptide binding].
 
    0.930
GAK48612.1
Sugar phosphatase isomerase/epimerase; Xylose isomerase-like TIM barrel; pfam01261; gene_1710; identified by MetaGeneAnnotator; putative; sugar phosphate isomerase/epimerase [Lactobacillus buchneri CD034].
 
    0.927
GAK48611.1
Gluconate:proton symporter; Citrate transporter [Lactobacillus buchneri CD034]; gene_1709; identified by MetaGeneAnnotator; putative.
 
     0.925
kdgK
2-dehydro-3-deoxygluconokinase [Lactobacillus buchneri CD034]; 2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the..; cd01166; ATP binding site [chemical binding]; Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; COG0524; gene_1708; identified by MetaGeneAnnotator; putative; substrate binding site [chemical binding].
 
    0.856
GAK48606.1
Transcriptional regulator; DNA binding site [nucleotide binding]; Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; cd01392; Ligand-binding domain of DNA transcription repressor RegR and other putative regulators such as KdgR and EndR; cd06283; Transcriptional regulators [Transcription]; COG1609; domain linker motif; gene_1704; identified by MetaGeneAnnotator; putative; putative dimerization interface [polypeptide binding]; putative ligand binding site [chemical binding]; transcriptional regulator [Lactobacillus brevis ATCC 367].
 
     0.744
GAK48613.1
Hypothetical protein; Gene_1711; identified by MetaGeneAnnotator; putative.
       0.663
rpe
COG0036 [G] Pentose-5-phosphate-3-epimerase; Pentose-5-phosphate-3-epimerase [Carbohydrate transport and metabolism]; COG0036; Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose..; cd00429; gene_16; hexamer interface [polypeptide binding]; identified by MetaGeneAnnotator; putative; metal binding site [ion binding]; ribulose-phosphate 3-epimerase [Lactobacillus salivarius UCC118]; subst [...]
  
 
 0.598
rpiA
Ribose-5-phosphate isomerase A; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
    
 0.504
Your Current Organism:
Lactobacillus oryzae
NCBI taxonomy Id: 1291743
Other names: L. oryzae JCM 18671, Lactobacillus oryzae JCM 18671, Lactobacillus oryzae SG293, Lactobacillus sp. JCM 18671, Lactobacillus sp. SG293
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