node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
GAK48397.1 | GAK48691.1 | LOSG293_280060 | LOSG293_490050 | Hypothetical protein; Gene_1495; identified by MetaGeneAnnotator; putative. | Phage integrase; DNA binding site [nucleotide binding]; DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site..; cl00213; Int/Topo IB signature motif; gene_1789; identified by MetaGeneAnnotator; putative; integrase [Lactobacillus reuteri SD2112]. | 0.423 |
GAK48691.1 | GAK48397.1 | LOSG293_490050 | LOSG293_280060 | Phage integrase; DNA binding site [nucleotide binding]; DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site..; cl00213; Int/Topo IB signature motif; gene_1789; identified by MetaGeneAnnotator; putative; integrase [Lactobacillus reuteri SD2112]. | Hypothetical protein; Gene_1495; identified by MetaGeneAnnotator; putative. | 0.423 |
GAK48691.1 | GAK48692.1 | LOSG293_490050 | LOSG293_490060 | Phage integrase; DNA binding site [nucleotide binding]; DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site..; cl00213; Int/Topo IB signature motif; gene_1789; identified by MetaGeneAnnotator; putative; integrase [Lactobacillus reuteri SD2112]. | AbrB family transcriptional regulator [Pediococcus claussenii ATCC BAA- 344]; Antidote-toxin recognition MazE; cl00877; gene_1790; identified by MetaGeneAnnotator; putative. | 0.561 |
GAK48691.1 | GAK48693.1 | LOSG293_490050 | LOSG293_490070 | Phage integrase; DNA binding site [nucleotide binding]; DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site..; cl00213; Int/Topo IB signature motif; gene_1789; identified by MetaGeneAnnotator; putative; integrase [Lactobacillus reuteri SD2112]. | PemK-like protein; pfam02452; gene_1791; identified by MetaGeneAnnotator; putative; pemK-like family protein [Pediococcus claussenii ATCC BAA- 344]. | 0.557 |
GAK48691.1 | hslV | LOSG293_490050 | LOSG293_120300 | Phage integrase; DNA binding site [nucleotide binding]; DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site..; cl00213; Int/Topo IB signature motif; gene_1789; identified by MetaGeneAnnotator; putative; integrase [Lactobacillus reuteri SD2112]. | ATP-dependent protease subunit HslV; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. | 0.414 |
GAK48691.1 | topA | LOSG293_490050 | LOSG293_120020 | Phage integrase; DNA binding site [nucleotide binding]; DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site..; cl00213; Int/Topo IB signature motif; gene_1789; identified by MetaGeneAnnotator; putative; integrase [Lactobacillus reuteri SD2112]. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.455 |
GAK48692.1 | GAK48691.1 | LOSG293_490060 | LOSG293_490050 | AbrB family transcriptional regulator [Pediococcus claussenii ATCC BAA- 344]; Antidote-toxin recognition MazE; cl00877; gene_1790; identified by MetaGeneAnnotator; putative. | Phage integrase; DNA binding site [nucleotide binding]; DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site..; cl00213; Int/Topo IB signature motif; gene_1789; identified by MetaGeneAnnotator; putative; integrase [Lactobacillus reuteri SD2112]. | 0.561 |
GAK48692.1 | GAK48693.1 | LOSG293_490060 | LOSG293_490070 | AbrB family transcriptional regulator [Pediococcus claussenii ATCC BAA- 344]; Antidote-toxin recognition MazE; cl00877; gene_1790; identified by MetaGeneAnnotator; putative. | PemK-like protein; pfam02452; gene_1791; identified by MetaGeneAnnotator; putative; pemK-like family protein [Pediococcus claussenii ATCC BAA- 344]. | 0.783 |
GAK48693.1 | GAK48691.1 | LOSG293_490070 | LOSG293_490050 | PemK-like protein; pfam02452; gene_1791; identified by MetaGeneAnnotator; putative; pemK-like family protein [Pediococcus claussenii ATCC BAA- 344]. | Phage integrase; DNA binding site [nucleotide binding]; DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site..; cl00213; Int/Topo IB signature motif; gene_1789; identified by MetaGeneAnnotator; putative; integrase [Lactobacillus reuteri SD2112]. | 0.557 |
GAK48693.1 | GAK48692.1 | LOSG293_490070 | LOSG293_490060 | PemK-like protein; pfam02452; gene_1791; identified by MetaGeneAnnotator; putative; pemK-like family protein [Pediococcus claussenii ATCC BAA- 344]. | AbrB family transcriptional regulator [Pediococcus claussenii ATCC BAA- 344]; Antidote-toxin recognition MazE; cl00877; gene_1790; identified by MetaGeneAnnotator; putative. | 0.783 |
hslV | GAK48691.1 | LOSG293_120300 | LOSG293_490050 | ATP-dependent protease subunit HslV; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. | Phage integrase; DNA binding site [nucleotide binding]; DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site..; cl00213; Int/Topo IB signature motif; gene_1789; identified by MetaGeneAnnotator; putative; integrase [Lactobacillus reuteri SD2112]. | 0.414 |
hslV | topA | LOSG293_120300 | LOSG293_120020 | ATP-dependent protease subunit HslV; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.465 |
topA | GAK48691.1 | LOSG293_120020 | LOSG293_490050 | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | Phage integrase; DNA binding site [nucleotide binding]; DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site..; cl00213; Int/Topo IB signature motif; gene_1789; identified by MetaGeneAnnotator; putative; integrase [Lactobacillus reuteri SD2112]. | 0.455 |
topA | hslV | LOSG293_120020 | LOSG293_120300 | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | ATP-dependent protease subunit HslV; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. | 0.465 |