STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GAK48755.1Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo..; cd00027; Dimer interface [polypeptide binding]; Hypothetical cytosolic protein [Lactobacillus rhamnosus HN001]; gene_1853; identified by MetaGeneAnnotator; putative. (99 aa)    
Predicted Functional Partners:
leuS
leucyl-tRNA synthetase; Anticodon-binding domain of bacterial and eukaryotic mitochondrial leucyl tRNA synthetases; cd07958; Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; cl12020; HIGH motif; KEGG: lbr:LVIS_1062 0. leuS; leucyl-tRNA synthetase K01869; Psort location: Cytoplasmic, score: 9.97; KMSKS motif; Leucyl-tRNA synthetase, Domain 2; pfam13603; catalytic core domain of leucyl-tRNA synthetases; cd00812; gene_149; identified by MetaGeneAnnotator; putative; leucine--tRNA ligase [Lactobacillus parafarraginis F0439]; leucyl-tRNA synthetase; Valida [...]
   
 
 0.796
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
   
 
 0.787
GAK48756.1
Site-specific recombinase, resolvase family; DNA binding site [nucleotide binding]; DNA-binding interface [nucleotide binding]; Helix-turn-helix domains; cl00088; Presynaptic Site I dimer interface [polypeptide binding]; Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and..; cd03768; Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; COG1961; [...]
       0.774
GAK46922.1
tRNA and rRNA cytosine-C5-methylase; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.
  
  
 0.679
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
     
 0.602
GAK48415.1
CamS sex pheromone cAM373 family protein [Lactobacillus buchneri NRRL B- 30929]; CamS sex pheromone cAM373 precursor; pfam07537; PFAM: CamS sex pheromone cAM373; KEGG: lbr:LVIS_1632 hypothetical protein; Signal predicted by SignalP 3.0 HMM (Signal peptide probability 0.939) with cleavage site probability 0.743 at residue 22; gene_1513; identified by MetaGeneAnnotator; putative.
  
  
 0.532
dnaE
DNA polymerase III subunit alpha; Gene_527; identified by MetaGeneAnnotator; putative.
    
 0.488
uvrC
Excinuclease ABC subunit C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
    
 0.486
GAK48757.1
Transposase; Gene_1855; identified by MetaGeneAnnotator; putative; transposase [Lactobacillus reuteri JCM 1112].
       0.483
GAK48582.1
Recombination protein RecJ; Gene_1680; identified by MetaGeneAnnotator; putative.
  
  
 0.477
Your Current Organism:
Lactobacillus oryzae
NCBI taxonomy Id: 1291743
Other names: L. oryzae JCM 18671, Lactobacillus oryzae JCM 18671, Lactobacillus oryzae SG293, Lactobacillus sp. JCM 18671, Lactobacillus sp. SG293
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