| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| KIR11662.1 | cobA | SH09_04690 | SH09_00565 | Uroporphyrinogen III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | uroporphyrin-III methyltransferase; Catalyzes 2 sequential methylations, the formation of precorrin-1 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and uroporphyrin III, and the formation of precorrin-2 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and precorrin-1; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.953 |
| KIR11662.1 | cysG_2 | SH09_04690 | SH09_08745 | Uroporphyrinogen III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | uroporphyrin-III methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the precorrin methyltransferase family. | 0.952 |
| KIR11662.1 | hemB | SH09_04690 | SH09_04695 | Uroporphyrinogen III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Delta-aminolevulinic acid dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ALAD family. | 0.995 |
| KIR11662.1 | hemC_2 | SH09_04690 | SH09_04685 | Uroporphyrinogen III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Porphobilinogen deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.999 |
| KIR11662.1 | hemE_1 | SH09_04690 | SH09_12835 | Uroporphyrinogen III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Uroporphyrinogen decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the uroporphyrinogen decarboxylase family. | 0.957 |
| KIR11662.1 | sirA | SH09_04690 | SH09_08730 | Uroporphyrinogen III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Preprotein translocase subunit TatB; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.479 |
| KIR11662.1 | sirC | SH09_04690 | SH09_00555 | Uroporphyrinogen III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Precorrin-2 dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.708 |
| cbiX | cobA | SH09_00560 | SH09_00565 | Sirohydrochlorin ferrochelatase; Derived by automated computational analysis using gene prediction method: Protein Homology. | uroporphyrin-III methyltransferase; Catalyzes 2 sequential methylations, the formation of precorrin-1 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and uroporphyrin III, and the formation of precorrin-2 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and precorrin-1; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.950 |
| cbiX | cysG_2 | SH09_00560 | SH09_08745 | Sirohydrochlorin ferrochelatase; Derived by automated computational analysis using gene prediction method: Protein Homology. | uroporphyrin-III methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the precorrin methyltransferase family. | 0.767 |
| cbiX | cysH | SH09_00560 | SH09_00580 | Sirohydrochlorin ferrochelatase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Phosphoadenosine phosphosulfate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.802 |
| cbiX | cysI_2 | SH09_00560 | SH09_00570 | Sirohydrochlorin ferrochelatase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Sulfite reductase; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. | 0.772 |
| cbiX | sirA | SH09_00560 | SH09_08730 | Sirohydrochlorin ferrochelatase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Preprotein translocase subunit TatB; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.970 |
| cbiX | sirC | SH09_00560 | SH09_00555 | Sirohydrochlorin ferrochelatase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Precorrin-2 dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.991 |
| cobA | KIR11662.1 | SH09_00565 | SH09_04690 | uroporphyrin-III methyltransferase; Catalyzes 2 sequential methylations, the formation of precorrin-1 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and uroporphyrin III, and the formation of precorrin-2 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and precorrin-1; Derived by automated computational analysis using gene prediction method: Protein Homology. | Uroporphyrinogen III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | 0.953 |
| cobA | cbiX | SH09_00565 | SH09_00560 | uroporphyrin-III methyltransferase; Catalyzes 2 sequential methylations, the formation of precorrin-1 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and uroporphyrin III, and the formation of precorrin-2 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and precorrin-1; Derived by automated computational analysis using gene prediction method: Protein Homology. | Sirohydrochlorin ferrochelatase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.950 |
| cobA | cysG_2 | SH09_00565 | SH09_08745 | uroporphyrin-III methyltransferase; Catalyzes 2 sequential methylations, the formation of precorrin-1 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and uroporphyrin III, and the formation of precorrin-2 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and precorrin-1; Derived by automated computational analysis using gene prediction method: Protein Homology. | uroporphyrin-III methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the precorrin methyltransferase family. | 0.913 |
| cobA | cysH | SH09_00565 | SH09_00580 | uroporphyrin-III methyltransferase; Catalyzes 2 sequential methylations, the formation of precorrin-1 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and uroporphyrin III, and the formation of precorrin-2 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and precorrin-1; Derived by automated computational analysis using gene prediction method: Protein Homology. | Phosphoadenosine phosphosulfate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.888 |
| cobA | cysI_2 | SH09_00565 | SH09_00570 | uroporphyrin-III methyltransferase; Catalyzes 2 sequential methylations, the formation of precorrin-1 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and uroporphyrin III, and the formation of precorrin-2 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and precorrin-1; Derived by automated computational analysis using gene prediction method: Protein Homology. | Sulfite reductase; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. | 0.940 |
| cobA | hemB | SH09_00565 | SH09_04695 | uroporphyrin-III methyltransferase; Catalyzes 2 sequential methylations, the formation of precorrin-1 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and uroporphyrin III, and the formation of precorrin-2 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and precorrin-1; Derived by automated computational analysis using gene prediction method: Protein Homology. | Delta-aminolevulinic acid dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ALAD family. | 0.829 |
| cobA | hemC_2 | SH09_00565 | SH09_04685 | uroporphyrin-III methyltransferase; Catalyzes 2 sequential methylations, the formation of precorrin-1 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and uroporphyrin III, and the formation of precorrin-2 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and precorrin-1; Derived by automated computational analysis using gene prediction method: Protein Homology. | Porphobilinogen deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.987 |
