Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-occurrence
Co-expression
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[Homology]
Score
spsB_1Signal peptidase IB; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S26 family. (194 aa)    
Predicted Functional Partners:
lepB
Signal peptidase I; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S26 family.
  
  
 
0.917
spsB_3
Signal peptidase IB; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S26 family.
  
  
 
0.905
lepA_3
Elongation factor 4; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner.
  
 
 0.709
rnhB
Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
 
    0.618
secDF_2
Preprotein translocase subunit SecD; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.517
KIR12765.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.495
rseP
Zinc metalloprotease; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.495
gltB_1
Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.459
KIR12767.1
Cobalamin biosynthesis protein CobW; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.443
pbpX_2
Penicillin-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.442
Your Current Organism:
Staphylococcus gallinarum
NCBI taxonomy Id: 1293
Other names: ATCC 35539, CCM 3572, CCUG 15600, CIP 103504, DSM 20610, LMG 19121, LMG:19121, NCTC 12195, NRRL B-14763, S. gallinarum, strain VIII1
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