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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pdxTGlutamine amidotransferase; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. (191 aa)    
Predicted Functional Partners:
pdxS
Pyridoxal biosynthesis protein; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family.
 0.999
thiD
Pyridoxal kinase; Catalyzes the phosphorylation of three vitamin B6 precursors, pyridoxal, pyridoxine and pyridoxamine; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.887
tal
Transaldolase; Similar to novel fructose-6-phosphate aldolase from Escherichia coli; enzyme from Methanocaldococcus janaschii shows transaldolase activity; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.883
rbsK_1
Ribokinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.874
gabR_1
GntR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.602
rpe
Ribulose-phosphate 3-epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.469
pgi_2
Glucose-6-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.466
rbsR
LacI family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  0.445
ccpA_1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  0.445
ccpA_2
Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  0.445
Your Current Organism:
Staphylococcus gallinarum
NCBI taxonomy Id: 1293
Other names: ATCC 35539, CCM 3572, CCUG 15600, CIP 103504, DSM 20610, LMG 19121, LMG:19121, NCTC 12195, NRRL B-14763, S. gallinarum, strain VIII1
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