Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
KIR12280.12-amino-3-ketobutyrate CoA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (396 aa)    
Predicted Functional Partners:
glyA_2
Serine hydroxymethyltransferase; Catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.907
gcvPA
Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
  
 
 0.906
gcvPB
Glycine dehydrogenase; Acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; forms a heterodimer with subunit 1 to form the P protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.906
ltaE
Threonine aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.905
soxA_2
Methyltryptophan oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.904
KIR12339.1
UDP-glucose 4-epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.871
pucG_2
Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.800
bioD_1
ATP-dependent dethiobiotin synthetase BioD; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.762
amaA
N-acetyl-L,L-diaminopimelate deacetylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.712
bioK_1
Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Catalyzes the formation of S-adenosyl-4-methylthionine-2-oxobutanoate and 7,8-diaminononanoate from S-adenosyl-L-methionine and 8-amino-7-oxononanoate; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.640
Your Current Organism:
Staphylococcus gallinarum
NCBI taxonomy Id: 1293
Other names: ATCC 35539, CCM 3572, CCUG 15600, CIP 103504, DSM 20610, LMG 19121, LMG:19121, NCTC 12195, NRRL B-14763, S. gallinarum, strain VIII1
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