STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
dosCMembrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (356 aa)    
Predicted Functional Partners:
rsbW
Serine/threonine protein kinase; Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B).
   
 
 0.685
rsbU
Serine/threonine protein phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.535
secDF_2
Preprotein translocase subunit SecD; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.475
wecA
UDP-phosphate N-acetylglucosaminyl 1-phosphate transferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.458
KIR12566.1
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.455
vraS_1
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.455
yjjP_1
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.453
pepT_1
Peptidase T; Cleaves the N-terminal amino acid of tripeptides. Belongs to the peptidase M20B family.
       0.452
phoP_2
PhoP family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
  
 0.423
Your Current Organism:
Staphylococcus gallinarum
NCBI taxonomy Id: 1293
Other names: ATCC 35539, CCM 3572, CCUG 15600, CIP 103504, DSM 20610, LMG 19121, LMG:19121, NCTC 12195, NRRL B-14763, S. gallinarum, strain VIII1
Server load: medium (42%) [HD]