STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yfbRHydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (213 aa)    
Predicted Functional Partners:
KIR12532.1
Protein CsbA; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.886
uvrB_4
Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...]
       0.739
uvrA_1
Excinuclease ABC subunit A; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.739
prfB_1
Peptide chain release factor 2; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.647
KIR12530.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.628
yfkN
5'-nucleotidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.545
KIR12212.1
Dipeptidyl aminopeptidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
  0.487
deoD
Purine nucleoside phosphorylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.476
tmk
Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.
  
 
  0.466
tdk
Thymidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.465
Your Current Organism:
Staphylococcus gallinarum
NCBI taxonomy Id: 1293
Other names: ATCC 35539, CCM 3572, CCUG 15600, CIP 103504, DSM 20610, LMG 19121, LMG:19121, NCTC 12195, NRRL B-14763, S. gallinarum, strain VIII1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.