uvrB_4 protein (Staphylococcus gallinarum) - STRING interaction network

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uvrB_4

Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] (660 aa)

Predicted Functional Partners:

uvrA_1

0.999

uvrC_4

0.993

uvrA_4

0.989

pcrA

0.921

yfbR

0.739

KIR12532.1

0.739

hprK_2

0.648

trxB

0.648

lgt_2

0.636

KIR12567.1

0.600

Your Current Organism:

Staphylococcus gallinarum

NCBI taxonomy Id: 1293
Other names: ATCC 35539, CCM 3572, CCUG 15600, CIP 103504, DSM 20610, LMG 19121, LMG:19121, NCTC 12195, NRRL B-14763, S. gallinarum, strain VIII1

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
KIR12532.1	uvrA_1	SH09_03475	SH09_03485	Protein CsbA; Derived by automated computational analysis using gene prediction method: Protein Homology.	Excinuclease ABC subunit A; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.739
KIR12532.1	uvrB_4	SH09_03475	SH09_03480	Protein CsbA; Derived by automated computational analysis using gene prediction method: Protein Homology.	Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...]	0.739
KIR12532.1	yfbR	SH09_03475	SH09_03470	Protein CsbA; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.886
KIR12567.1	hprK_2	SH09_03500	SH09_03490	Acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Serine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.866
KIR12567.1	lgt_2	SH09_03500	SH09_03495	Acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.	0.872
KIR12567.1	trxB	SH09_03500	SH09_03510	Acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Thioredoxin reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.786
KIR12567.1	uvrA_1	SH09_03500	SH09_03485	Acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Excinuclease ABC subunit A; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.581
KIR12567.1	uvrB_4	SH09_03500	SH09_03480	Acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...]	0.600
hprK_2	KIR12567.1	SH09_03490	SH09_03500	Serine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.866
hprK_2	lgt_2	SH09_03490	SH09_03495	Serine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.	0.946
hprK_2	trxB	SH09_03490	SH09_03510	Serine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Thioredoxin reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.800
hprK_2	uvrA_1	SH09_03490	SH09_03485	Serine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Excinuclease ABC subunit A; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.621
hprK_2	uvrB_4	SH09_03490	SH09_03480	Serine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...]	0.648
lgt_2	KIR12567.1	SH09_03495	SH09_03500	Diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.	Acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.872
lgt_2	hprK_2	SH09_03495	SH09_03490	Diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.	Serine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.946
lgt_2	trxB	SH09_03495	SH09_03510	Diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.	Thioredoxin reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.783
lgt_2	uvrA_1	SH09_03495	SH09_03485	Diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.	Excinuclease ABC subunit A; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.581
lgt_2	uvrB_4	SH09_03495	SH09_03480	Diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.	Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...]	0.636
pcrA	uvrA_1	SH09_08340	SH09_03485	ATP-dependent DNA helicase PcrA; Derived by automated computational analysis using gene prediction method: Protein Homology.	Excinuclease ABC subunit A; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.780
pcrA	uvrA_4	SH09_08340	SH09_07320	ATP-dependent DNA helicase PcrA; Derived by automated computational analysis using gene prediction method: Protein Homology.	Daunorubicin resistance protein DrrC; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.717

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