Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
ezrA_2Septation ring formation regulator EzrA; Derived by automated computational analysis using gene prediction method: Protein Homology. (563 aa)    
Predicted Functional Partners:
gpsB
Cell division protein GpsB; Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation.
  
 
 0.927
pbpH_2
Penicillin-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
 0.859
ftsA_3
Cell division protein FtsA; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.849
mreD
Rod shape-determining protein MreD; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.833
KIR11621.1
Adenine methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.805
ftsZ_2
Cell division protein FtsZ; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 
 0.767
KIR11595.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.766
KIR11351.1
Lipoprotein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.743
KIR10808.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.742
KIR10517.1
Multidrug ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
 0.740
Your Current Organism:
Staphylococcus gallinarum
NCBI taxonomy Id: 1293
Other names: ATCC 35539, CCM 3572, CCUG 15600, CIP 103504, DSM 20610, LMG 19121, LMG:19121, NCTC 12195, NRRL B-14763, S. gallinarum, strain VIII1
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