Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (399 aa)    
Predicted Functional Partners:
eutD
Phosphotransacetylase; In Salmonella this enzyme is required for ethanolamine catabolism; has higher affinity for CoA than Pta; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.997
KIR11804.1
Phosphate butyryltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.953
pox5
Pyruvate oxidase; Catalyzes the formation of acetyl phosphate from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TPP enzyme family.
    
 0.932
acyP
Acylphosphatase; Catalyzes the hydrolysis of acylphosphate; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.915
hcl
acyl--CoA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.913
acsA_3
acetyl-CoA synthetase; Acs; catalyzes the conversion of acetate and CoA to acetyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.913
ctfA
CoA-transferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the 3-oxoacid CoA-transferase family.
     
 0.911
aldA_1
Aldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family.
    
 0.905
betB
Betaine-aldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family.
    
 0.905
KIR11061.1
Aldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family.
    
 0.905
Your Current Organism:
Staphylococcus gallinarum
NCBI taxonomy Id: 1293
Other names: ATCC 35539, CCM 3572, CCUG 15600, CIP 103504, DSM 20610, LMG 19121, LMG:19121, NCTC 12195, NRRL B-14763, S. gallinarum, strain VIII1
Server load: low (24%) [HD]