Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
dnaIPrimosomal protein DnaI; Derived by automated computational analysis using gene prediction method: Protein Homology. (307 aa)    
Predicted Functional Partners:
dnaB_1
Helicase DnaB; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.973
nrdR
Transcriptional regulator NrdR; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes.
       0.863
dnaD
Chromosome replication protein DnaD; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.839
dnaC_1
DNA helicase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.761
dnaC_4
Damage-inducible protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.761
dnaC_5
Damage-inducible protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.761
dnaA_3
Chromosomal replication initiation protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 
 0.687
mutM
formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
 
  
 0.673
KIR12525.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.668
thrS
threonyl-tRNA synthase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).
       0.645
Your Current Organism:
Staphylococcus gallinarum
NCBI taxonomy Id: 1293
Other names: ATCC 35539, CCM 3572, CCUG 15600, CIP 103504, DSM 20610, LMG 19121, LMG:19121, NCTC 12195, NRRL B-14763, S. gallinarum, strain VIII1
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