Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
fgs_1Folylpolyglutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (420 aa)    
Predicted Functional Partners:
folP_1
Dihydropteroate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.998
folA
Dihydrofolate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.952
valS
valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.921
thyA_1
Thymidylate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.857
folK_2
2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.840
folB
Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.
  
  
 0.816
folD
Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.
 
   
 0.642
fhs_1
Formate--tetrahydrofolate ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the formate--tetrahydrofolate ligase family.
  
 
 0.620
ribD_2
Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.595
guaA_1
GMP synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.569
Your Current Organism:
Staphylococcus gallinarum
NCBI taxonomy Id: 1293
Other names: ATCC 35539, CCM 3572, CCUG 15600, CIP 103504, DSM 20610, LMG 19121, LMG:19121, NCTC 12195, NRRL B-14763, S. gallinarum, strain VIII1
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