Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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[Homology]
Score
zapACell division protein ZapA; Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division. (88 aa)    
Predicted Functional Partners:
KIR12154.1
Colicin V production protein CvpA; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.954
ftsZ_2
Cell division protein FtsZ; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.851
ezrA_2
Septation ring formation regulator EzrA; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 
 0.739
polX_2
DNA polymerase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.730
sepF
Cell division protein SepF; Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
  
 
 
 0.726
ftsA_3
Cell division protein FtsA; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.684
rnhC_2
Ribonuclease HIII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.
  
    0.666
trxA_3
Thioredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.646
KIR11315.1
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.633
mutS2_2
Recombination and DNA strand exchange inhibitor protein; Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity. Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
       0.594
Your Current Organism:
Staphylococcus gallinarum
NCBI taxonomy Id: 1293
Other names: ATCC 35539, CCM 3572, CCUG 15600, CIP 103504, DSM 20610, LMG 19121, LMG:19121, NCTC 12195, NRRL B-14763, S. gallinarum, strain VIII1
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