Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
pdhA_1Pyruvate dehydrogenase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). (370 aa)    
Predicted Functional Partners:
pdhB_1
2-oxoisovalerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 0.999
bfmBAB_3
2-oxoisovalerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 0.998
pdhC_1
Branched-chain alpha-keto acid dehydrogenase subunit E2; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.997
lpdA
Dihydrolipoamide dehydrogenase; E3 component of pyruvate complex; catalyzes the oxidation of dihydrolipoamide to lipoamide; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.992
KIR11805.1
Dihydrolipoamide dehydrogenase; E3 component of the branched-chain alpha-keto acid dehydrogenase complex; catalyzes the oxidation of dihydrolipoamide to lipoamide; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.957
KIR12018.1
2-oxoglutarate ferredoxin oxidoreductase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.940
pyk
Pyruvate kinase; Catalyzes the formation of phosphoenolpyruvate from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.937
pdhC_3
2-oxoglutarate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.931
ldhA
Lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate.
   
 
 0.913
ppdK_1
Pyruvate phosphate dikinase; Catalyzes the formation of phosphoenolpyruvate from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.913
Your Current Organism:
Staphylococcus gallinarum
NCBI taxonomy Id: 1293
Other names: ATCC 35539, CCM 3572, CCUG 15600, CIP 103504, DSM 20610, LMG 19121, LMG:19121, NCTC 12195, NRRL B-14763, S. gallinarum, strain VIII1
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