Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
sirAPreprotein translocase subunit TatB; Derived by automated computational analysis using gene prediction method: Protein Homology. (154 aa)    
Predicted Functional Partners:
cysG_2
uroporphyrin-III methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the precorrin methyltransferase family.
 
 
 0.997
cobA
uroporphyrin-III methyltransferase; Catalyzes 2 sequential methylations, the formation of precorrin-1 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and uroporphyrin III, and the formation of precorrin-2 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and precorrin-1; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.989
cbiX
Sirohydrochlorin ferrochelatase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.970
nirR_2
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.937
sirC
Precorrin-2 dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 
0.926
nasE
Nitrite reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.903
nasD_2
Nitrite reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.877
hemC_2
Porphobilinogen deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.688
hemB
Delta-aminolevulinic acid dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ALAD family.
 
   
 0.687
hemA_2
glutamyl-tRNA reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.630
Your Current Organism:
Staphylococcus gallinarum
NCBI taxonomy Id: 1293
Other names: ATCC 35539, CCM 3572, CCUG 15600, CIP 103504, DSM 20610, LMG 19121, LMG:19121, NCTC 12195, NRRL B-14763, S. gallinarum, strain VIII1
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