close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nreCLuxR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (217 aa)    
Predicted Functional Partners:
nreB_2
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.998
vraS_1
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 0.990
desK
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.969
vraS_3
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.931
nreA_1
NreA; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.919
narZ
Nitrate reductase; With NarYV catalyzes the reduction of nitrate; the beta subunit is an iron sulfur cluster containing electron transfer subunit; one of 3 nitrate reductases in E. coli; expression of nitrate reductase Z is not dependent on nitrate levels; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.752
narJ
Nitrate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.752
graS
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.696
hssS_2
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.696
narI
Nitrate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.692
Your Current Organism:
Staphylococcus gallinarum
NCBI taxonomy Id: 1293
Other names: ATCC 35539, CCM 3572, CCUG 15600, CIP 103504, DSM 20610, LMG 19121, LMG:19121, NCTC 12195, NRRL B-14763, S. gallinarum, strain VIII1
Server load: medium (42%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.