Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
dltA_1Alanine-phosphoribitol ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (487 aa)    
Predicted Functional Partners:
dltB
D-alanine transfer protein DltB; Could be involved in the transport of activated D-alanine through the membrane.
 
 
 0.999
dltC
Alanine-phosphoribitol ligase; Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC- carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall.
 
 
 0.999
dltD
D-alanyl-lipoteichoic acid biosynthesis protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.999
ddl
D-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family.
   
 
 0.931
tycC_1
Long-chain fatty acid--CoA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
0.922
alr2
Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.
    
 0.922
alr1_1
Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.
    
 0.922
dat
D-alanine aminotransferase; Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha-keto acid in the first half-reaction.
   
 0.909
lytR_1
LytR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
  0.900
msrR_1
LytR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
  0.900
Your Current Organism:
Staphylococcus gallinarum
NCBI taxonomy Id: 1293
Other names: ATCC 35539, CCM 3572, CCUG 15600, CIP 103504, DSM 20610, LMG 19121, LMG:19121, NCTC 12195, NRRL B-14763, S. gallinarum, strain VIII1
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