Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
tplSignal peptidase II; Derived by automated computational analysis using gene prediction method: Protein Homology. (267 aa)    
Predicted Functional Partners:
dnaX_3
DNA polymerase III subunit delta; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   0.876
rny_1
Ribonuclease; Endoribonuclease that initiates mRNA decay.
 
  
 0.868
yabA
DNA replication protein YabA; Involved in initiation control of chromosome replication. Belongs to the YabA family.
  
    0.858
KIR10531.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.763
KIR10527.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.737
rsmI_2
16S rRNA methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.723
KIR12169.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0342 family.
 
   
 0.722
KIR10532.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.717
tmk
Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.
  
    0.690
speA_2
Lysine decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.687
Your Current Organism:
Staphylococcus gallinarum
NCBI taxonomy Id: 1293
Other names: ATCC 35539, CCM 3572, CCUG 15600, CIP 103504, DSM 20610, LMG 19121, LMG:19121, NCTC 12195, NRRL B-14763, S. gallinarum, strain VIII1
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.