Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
folP_1Dihydropteroate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (270 aa)    
Predicted Functional Partners:
folB
Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.
 
 
 0.999
folK_2
2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.999
fgs_1
Folylpolyglutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.998
KIR12487.1
Aminodeoxychorismate lyase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.917
birA_1
biotin--acetyl-CoA-carboxylase ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.716
KIR12145.1
Nucleoside-triphosphate diphosphatase; Hydrolyzes non-standard nucleotides such as xanthine and inosine; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.699
ribH
6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin; Belongs to the DMRL synthase family.
  
  
 0.678
ribD_2
Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.661
pabB
Aminobenzoate synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.651
dnaK
Molecular chaperone DnaK; Heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.647
Your Current Organism:
Staphylococcus gallinarum
NCBI taxonomy Id: 1293
Other names: ATCC 35539, CCM 3572, CCUG 15600, CIP 103504, DSM 20610, LMG 19121, LMG:19121, NCTC 12195, NRRL B-14763, S. gallinarum, strain VIII1
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