STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AAES_252648Lysine-specific demethylase hairless. (1452 aa)    
Predicted Functional Partners:
PPARG
Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]
    
 0.796
AAES_152729
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1; Belongs to the SNF5 family.
    
 0.776
AAES_158180
cAMP-dependent protein kinase catalytic subunit beta isoform X6; Belongs to the protein kinase superfamily.
   
 
  0.753
AAES_28147
Peroxisome proliferator-activated receptor alpha.
    
 0.592
AAES_124306
AT-rich interactive domain-containing protein 1B.
   
  0.580
AAES_16198
AT-rich interactive domain-containing protein 1A.
   
  0.580
AAES_42137
Transcription activator BRG1-like protein.
   
 
 0.569
AAES_166605
Putative global transcription activator SNF2L2 isoform X2.
   
 
 0.569
AAES_68942
SWI/SNF complex subunit SMARCC1-like protein.
   
 
 0.563
AAES_68955
Uncharacterized protein.
   
 
 0.563
Your Current Organism:
Amazona aestiva
NCBI taxonomy Id: 12930
Other names: A. aestiva, blue-fronted amazon
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.