STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AAES_130417RPOL4c domain-containing protein. (214 aa)    
Predicted Functional Partners:
AAES_70494
NA directed RNA polymerase II polypeptide E.
   
 0.994
AAES_74873
DNA-directed RNA polymerases I, II, and III subunit RPABC4.
   
 0.994
AAES_97767
DNA-directed RNA polymerases I, II, and III subunit RPABC5.
    
 0.993
AAES_213669
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 0.993
AAES_08009
DNA-directed RNA polymerase II subunit RPB3.
    
 0.993
AAES_06489
RNA polymerase-associated protein LEO1 isoform X1.
    
  0.993
AAES_167781
Transcription elongation factor SPT4; Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates transcription elongation by RNA polymerase II; Belongs to the SPT4 family.
   
 0.990
AAES_47707
Uncharacterized protein.
    
 0.990
AAES_153774
Transcription initiation factor IIB.
    
 0.989
AAES_75265
General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity.
   
 0.986
Your Current Organism:
Amazona aestiva
NCBI taxonomy Id: 12930
Other names: A. aestiva, blue-fronted amazon
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.