STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AAES_40644PAX-interacting protein 1 isoform X1. (1182 aa)    
Predicted Functional Partners:
AAES_163035
Tumor suppressor p53-binding protein 1 isoform X4.
    
 0.993
AAES_82063
Uncharacterized protein; Belongs to the PI3/PI4-kinase family.
   
 0.990
AAES_99911
Structural maintenance of chromosomes protein 6.
   
 
 0.989
AAES_71086
Ankyrin repeat domain-containing protein 32.
   
 0.987
AAES_144064
Nibrin; Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double- strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis.
    
 0.983
AAES_62895
Lysine-specific demethylase 6A isoform X2.
    
 0.948
AAES_74103
Set1/Ash2 histone methyltransferase complex subunit ASH2.
    
 0.938
AAES_44562
DNA topoisomerase 2-binding protein 1.
   
 
0.933
AAES_106911
Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.
    
 0.932
AAES_122250
Uncharacterized protein.
   
 0.929
Your Current Organism:
Amazona aestiva
NCBI taxonomy Id: 12930
Other names: A. aestiva, blue-fronted amazon
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.