STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AAES_240366Transmembrane protein. (270 aa)    
Predicted Functional Partners:
AAES_40467
Uncharacterized protein.
    
 
 0.996
AAES_01558
Protein unc-80 isoform X1.
    
 
 0.777
AAES_168664
FERM domain-containing protein.
   
 
 0.695
AAES_32945
Sodium leak channel non-selective protein-like protein.
   
 
 0.695
AAES_19669
Sodium leak channel non-selective protein-like protein.
   
 
 0.695
AAES_158784
Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
   
 
 0.461
AAES_122967
Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
   
 
 0.456
AAES_105368
Ion_trans domain-containing protein.
   
 
 0.456
AAES_105321
Voltage-dependent N-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1B gives rise to N-type calcium currents.
   
 
 0.456
AAES_63113
Two pore calcium channel protein 1.
   
 
 0.456
Your Current Organism:
Amazona aestiva
NCBI taxonomy Id: 12930
Other names: A. aestiva, blue-fronted amazon
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.