STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AAES_55531Inward rectifier potassium channel 2. (427 aa)    
Predicted Functional Partners:
AAES_136529
Inward rectifier potassium channel 4.
  
  
0.818
AAES_57644
Endothelin-1 receptor isoform X1; Belongs to the G-protein coupled receptor 1 family.
     
 0.803
AAES_06467
Guanine nucleotide-binding protein subunit beta-5.
    
  0.654
AAES_113338
ATP-binding cassette sub-family C member 9.
 
  
 0.654
AAES_26945
ATP-binding cassette sub-family C member 8-like protein.
 
  
 0.650
AAES_124045
Multidrug resistance-associated protein 4.
    
 0.643
AAES_100117
Multidrug resistance-associated protein 5-like protein.
    
 0.643
AAES_100145
Multidrug resistance-associated protein 5-like isoform X11.
    
 0.643
AAES_88289
Multidrug resistance-associated protein 1-like protein.
    
 0.643
AAES_87108
Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer.
    
 0.643
Your Current Organism:
Amazona aestiva
NCBI taxonomy Id: 12930
Other names: A. aestiva, blue-fronted amazon
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