STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nep1Unannotated protein; Methyltransferase involved in ribosomal biogenesis. Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA. (101 aa)    
Predicted Functional Partners:
DFR87_03005
Unannotated protein.
  
 0.983
rps4
Unannotated protein; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
   
  0.976
DFR87_07010
Unannotated protein.
   
 
 0.968
csl4
Unannotated protein; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs.
  
 0.965
rps6e
Unannotated protein; Belongs to the eukaryotic ribosomal protein eS6 family.
   
  0.963
DFR87_10050
Unannotated protein.
   
 
 0.963
rps11
Unannotated protein; Located on the platform of the 30S subunit. Belongs to the universal ribosomal protein uS11 family.
   
 0.962
rps7
Unannotated protein; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center; Belongs to the universal ribosomal protein uS7 family.
   
 0.962
rps3ae
Unannotated protein; Belongs to the eukaryotic ribosomal protein eS1 family.
   
  0.952
rps28e
Unannotated protein; Belongs to the eukaryotic ribosomal protein eS28 family.
   
 0.946
Your Current Organism:
Metallosphaera hakonensis
NCBI taxonomy Id: 1293036
Other names: M. hakonensis JCM 8857 = DSM 7519, Metallosphaera hakonensis DSM 7519, Metallosphaera hakonensis DSM 7519 = JCM 8857, Metallosphaera hakonensis HO1-1, Metallosphaera hakonensis JCM 8857, Metallosphaera hakonensis JCM 8857 = DSM 7519
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.