STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
H663_16875Lactoylglutathione lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (164 aa)    
Predicted Functional Partners:
trpB
Tryptophan synthase subunit alpha; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
   
  0.908
H663_03580
2-hydroxyacid dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
   
 0.902
H663_03310
Amino acid deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
  0.896
ilvA
Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
   
 
 0.895
H663_16830
methylmalonyl-CoA mutase; MDM; functions in conversion of succinate to propionate; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.817
icmF
methylmalonyl-CoA mutase; Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly.
  
 
 0.785
H663_16870
acetyl-CoA carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.727
H663_06025
CDP-6-deoxy-delta-3,4-glucoseen reductase; Catalyzes the formation of 3,6-dideoxy-D-glycero-D-glycero-4-hexulose; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.592
H663_16855
methylmalonyl-CoA carboxyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.563
H663_03345
Catalase; Serves to protect cells from the toxic effects of hydrogen peroxide.
   
 
 0.540
Your Current Organism:
Limnohabitans planktonicus
NCBI taxonomy Id: 1293045
Other names: L. planktonicus II-D5, Limnohabitans planktonicus II-D5, beta proteobacterium II-D5
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