STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AMX83454.1Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (334 aa)    
Predicted Functional Partners:
iolB
5-deoxy-glucuronate isomerase; Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D-gluconate).
 
  
 0.884
iolC
5-dehydro-2-deoxygluconokinase; Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5-dehydro-2- deoxy-D-gluconate (DKGP).
 
  
 0.877
iolD
3D-(3,5/4)-trihydroxycyclohexane-1,2-dione acylhydrolase (decyclizing); Involved in the cleavage of the C1-C2 bond of 3D-(3,5/4)- trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy-glucuronate (5DG).
 
  
 0.871
AMX83462.1
Myo-inosose-2 dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.867
AMX82224.1
Sugar phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.821
AMX83455.1
Dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    
0.799
AMX83460.1
Isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.716
AMX83456.1
Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    
0.678
AMX82229.1
Xylose isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.656
AMX83328.1
Xylose isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.650
Your Current Organism:
Geobacillus subterraneus
NCBI taxonomy Id: 129338
Other names: AS 12673, DSM 13552, Geobacillus subterraneus Nazina et al. 2001 emend. Poli et al. 2013, KCTC 3922, VKM B-2226, strain 34
Server load: low (14%) [HD]