STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AMX85286.1Resolvase; Derived by automated computational analysis using gene prediction method: Protein Homology. (216 aa)    
Predicted Functional Partners:
yneA
Peptigoglycan-binding protein LysM; Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and/or DivIC to the division machinery; Belongs to the YneA family.
  
  
 0.886
AMX83936.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.738
AMX83920.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.714
AMX84196.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.708
lexA
XRE family transcriptional regulator; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
  
  
 0.705
AMX85107.1
EpuA protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.669
AMX83552.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.642
AMX82568.1
Peptidase M4; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.640
yjjX
NTPase; Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.
  
    0.570
AMX83339.1
Rhodanese; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.548
Your Current Organism:
Geobacillus subterraneus
NCBI taxonomy Id: 129338
Other names: AS 12673, DSM 13552, Geobacillus subterraneus Nazina et al. 2001 emend. Poli et al. 2013, KCTC 3922, VKM B-2226, strain 34
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.