node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
KKC35110.1 | KKC35487.1 | WH87_18385 | WH87_15530 | Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. | Converts isocitrate to alpha ketoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the isocitrate and isopropylmalate dehydrogenases family. | 0.988 |
KKC35110.1 | KKC38720.1 | WH87_18385 | WH87_07280 | Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. | Citrate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.984 |
KKC35110.1 | KKC38721.1 | WH87_18385 | WH87_07285 | Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. | Citrate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the citrate synthase family. | 0.987 |
KKC35110.1 | KKC39754.1 | WH87_18385 | WH87_06345 | Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. | Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. | 0.960 |
KKC35110.1 | KKC39847.1 | WH87_18385 | WH87_06950 | Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. | Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. | 0.960 |
KKC35110.1 | KKC41022.1 | WH87_18385 | WH87_02430 | Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. | 3-hydroxyacyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the enoyl-CoA hydratase/isomerase family. | 0.977 |
KKC35110.1 | gltA | WH87_18385 | WH87_03670 | Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. | Type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the citrate synthase family. | 0.985 |
KKC35110.1 | rplB | WH87_18385 | WH87_04070 | Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. | 50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. | 0.954 |
KKC35110.1 | rplE | WH87_18385 | WH87_04025 | Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. | 50S ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. | 0.956 |
KKC35110.1 | rpsH | WH87_18385 | WH87_04015 | Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. | 30S ribosomal protein S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family. | 0.954 |
KKC35487.1 | KKC35110.1 | WH87_15530 | WH87_18385 | Converts isocitrate to alpha ketoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the isocitrate and isopropylmalate dehydrogenases family. | Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. | 0.988 |
KKC35487.1 | KKC38720.1 | WH87_15530 | WH87_07280 | Converts isocitrate to alpha ketoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the isocitrate and isopropylmalate dehydrogenases family. | Citrate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.823 |
KKC35487.1 | KKC38721.1 | WH87_15530 | WH87_07285 | Converts isocitrate to alpha ketoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the isocitrate and isopropylmalate dehydrogenases family. | Citrate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the citrate synthase family. | 0.823 |
KKC35487.1 | KKC39754.1 | WH87_15530 | WH87_06345 | Converts isocitrate to alpha ketoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the isocitrate and isopropylmalate dehydrogenases family. | Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. | 0.650 |
KKC35487.1 | KKC39847.1 | WH87_15530 | WH87_06950 | Converts isocitrate to alpha ketoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the isocitrate and isopropylmalate dehydrogenases family. | Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. | 0.650 |
KKC35487.1 | KKC41022.1 | WH87_15530 | WH87_02430 | Converts isocitrate to alpha ketoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the isocitrate and isopropylmalate dehydrogenases family. | 3-hydroxyacyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the enoyl-CoA hydratase/isomerase family. | 0.788 |
KKC35487.1 | gltA | WH87_15530 | WH87_03670 | Converts isocitrate to alpha ketoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the isocitrate and isopropylmalate dehydrogenases family. | Type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the citrate synthase family. | 0.823 |
KKC38720.1 | KKC35110.1 | WH87_07280 | WH87_18385 | Citrate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. | 0.984 |
KKC38720.1 | KKC35487.1 | WH87_07280 | WH87_15530 | Citrate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Converts isocitrate to alpha ketoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the isocitrate and isopropylmalate dehydrogenases family. | 0.823 |
KKC38720.1 | KKC38721.1 | WH87_07280 | WH87_07285 | Citrate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Citrate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the citrate synthase family. | 0.929 |