STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Gene Fusion
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[Homology]
Score
dltAD-alanine--poly(phosphoribitol) ligase subunit 1; Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D- alanyl carrier protein (Dcp) DltC. In an ATP-dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall. Belongs to [...] (500 aa)    
Predicted Functional Partners:
KRL00977.1
Protein DltB; Could be involved in the transport of activated D-alanine through the membrane.
  
 0.999
dltC
D-alanine--poly(phosphoribitol) ligase, subunit 2; Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC- carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall.
 
 0.999
KRL00979.1
DltD C-terminal domain protein.
 
  
 0.998
acpP
Hypothetical protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
  
 0.956
acpP-2
Hypothetical protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family.
  
 0.956
ddl
D-ala D-ala ligase N-terminal domain protein; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family.
   
 
 0.954
KRL01074.1
Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.
    
 0.944
KRL01458.1
Hypothetical protein.
   
 0.881
KRL03338.1
Oxidoreductase, short chain dehydrogenase reductase family protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
 
 
 0.864
KRL03419.1
3-oxoacyl-(acyl-carrier-protein) synthase ii; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.
 
 
 
 0.762
Your Current Organism:
Lactobacillus equicursoris
NCBI taxonomy Id: 1293597
Other names: L. equicursoris DSM 19284 = JCM 14600 = CIP 110162, Lactobacillus equicursoris CIP 110162, Lactobacillus equicursoris DI70, Lactobacillus equicursoris DSM 19284, Lactobacillus equicursoris DSM 19284 = JCM 14600 = CIP 110162, Lactobacillus equicursoris JCM 14600, Lactobacillus sp. DI70
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