STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KRL02952.1Hydrolase, NUDIX family. (146 aa)    
Predicted Functional Partners:
KRL03326.1
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 
  0.920
ribB
3,4-dihydroxy-2-butanone-4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the GTP cyclohydrolase II family. In the N-terminal section; belongs to the DHBP synthase family.
     
 0.902
KRL02953.1
Peptidase, M23 family.
       0.773
KRL02950.1
Nif3-like protein.
    
  0.712
guaA
Bifunctional gmp synthase glutamine amidotransferase; Catalyzes the synthesis of GMP from XMP.
    
  0.559
KRL02951.1
SAM-dependent methyltransferase.
       0.531
KRL00396.1
Nucleoside-triphosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
  
 
 0.506
KRL03337.1
5-nucleotidase, C-terminal domain protein; Belongs to the 5'-nucleotidase family.
 
  
  0.496
nadE
Nh(3)-dependent nad(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family.
  
 
 0.464
KRL02948.1
Peptidase T; Cleaves the N-terminal amino acid of tripeptides. Belongs to the peptidase M20B family.
       0.461
Your Current Organism:
Lactobacillus equicursoris
NCBI taxonomy Id: 1293597
Other names: L. equicursoris DSM 19284 = JCM 14600 = CIP 110162, Lactobacillus equicursoris CIP 110162, Lactobacillus equicursoris DI70, Lactobacillus equicursoris DSM 19284, Lactobacillus equicursoris DSM 19284 = JCM 14600 = CIP 110162, Lactobacillus equicursoris JCM 14600, Lactobacillus sp. DI70
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