STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
priAPrimosomal protein N (replication factor Y) - superfamily II helicase; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (801 aa)    
Predicted Functional Partners:
fmt
Methionyl-trna formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family.
    0.954
KRO18584.1
Phosphopantothenoylcysteinesynthetase decarboxyla se; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family.
  
    0.909
KRO16482.1
Single-stranded DNA-binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.
   
 
 0.885
KRO18587.1
tRNA and rRNA cytosine-C5-methytransferase; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.
  
    0.848
KRO18588.1
Phosphoprotein phosphatase.
  
    0.844
rsgA
GTPase; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
 
     0.832
KRO18589.1
Hypothetical protein.
       0.809
KRO18592.1
Thiamine pyrophosphokinase.
  
    0.763
KRO18591.1
Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family.
       0.756
KRO15932.1
Single-stranded DNA-specific exonuclease.
 
     0.729
Your Current Organism:
Lactobacillus saniviri
NCBI taxonomy Id: 1293598
Other names: L. saniviri JCM 17471 = DSM 24301, Lactobacillus saniviri DSM 24301, Lactobacillus saniviri DSM 24301 = JCM 17471, Lactobacillus saniviri JCM 17471, Lactobacillus saniviri JCM 17471 = DSM 24301, Lactobacillus saniviri YIT 12363, Lactobacillus sp. YIT 12363
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