STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
panUnannotated protein; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-20S proteasome [...] (244 aa)    
Predicted Functional Partners:
IC006_1935
Unannotated protein.
  
 0.972
psmA
Unannotated protein; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
  
 0.945
GCA_001316085_00250
Unannotated protein.
     0.909
GCA_001316085_00421
Unannotated protein.
   
 0.887
IC006_1609
Unannotated protein.
   
 0.887
psmB
Unannotated protein; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
  
 0.883
GCA_001316085_00243
Unannotated protein.
  
 0.883
psmB-2
Unannotated protein; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
  
 0.883
IC006_1768
Unannotated protein.
     
 0.806
IC006_1767
Unannotated protein.
       0.804
Your Current Organism:
Sulfolobus sp. JCM16833
NCBI taxonomy Id: 1294262
Other names: S. sp. JCM 16833, Sulfolobus sp. DSM 104736, Sulfolobus sp. JCM 16833
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.