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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AKS72450.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (259 aa)    
Predicted Functional Partners:
AKS72449.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.981
walK
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.951
AKS72451.1
Metallohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.943
walR
PhoP family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.907
ezrA
Septation ring formation regulator EzrA; Negative regulator of FtsZ ring formation; modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization; Belongs to the EzrA family.
  
     0.680
AKS72438.1
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.651
AKS74244.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.637
AKS72452.1
Methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.620
AKS74266.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.606
AKS73943.1
Cell division protein ZapA; Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.
  
     0.597
Your Current Organism:
Staphylococcus schleiferi
NCBI taxonomy Id: 1295
Other names: ATCC 43808, CCUG 25351, CIP 103643, DSM 4807, LMG 13347, LMG:13347, NCTC 12218, NRRL B-14775, S. schleiferi, strain N850274
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.