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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lrgAMurein hydrolase transporter LrgA; Derived by automated computational analysis using gene prediction method: Protein Homology. (144 aa)    
Predicted Functional Partners:
lrgB
Antiholin LrgB; Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like proteins CidA and/or CidB. The LrgAB and CidAB proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses; Belongs to the CidB/LrgB family. LrgB subfamily.
  
 0.996
AKS72802.1
Holin; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.947
lytR
Two-component response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.944
lytS
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.881
dhaK-2
With DhaL and DhaM forms dihydroxyacetone kinase, which is responsible for phosphorylating dihydroxyacetone; DhaK is the dihydroxyacetone binding subunit of the dihydroxyacetone kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.468
dhaL-2
Dihydroxyacetone kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.450
dhaM-2
PTS mannnose transporter subunit IIA; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.450
Your Current Organism:
Staphylococcus schleiferi
NCBI taxonomy Id: 1295
Other names: ATCC 43808, CCUG 25351, CIP 103643, DSM 4807, LMG 13347, LMG:13347, NCTC 12218, NRRL B-14775, S. schleiferi, strain N850274
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