| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AKS73489.1 | dnaK | RN70_06050 | RN70_06030 | 30S ribosomal protein S12 methylthiotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.754 |
| AKS73489.1 | grpE | RN70_06050 | RN70_06025 | 30S ribosomal protein S12 methylthiotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Heat shock protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- [...] | 0.701 |
| AKS73489.1 | hemN | RN70_06050 | RN70_06015 | 30S ribosomal protein S12 methylthiotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | 0.615 |
| AKS73489.1 | hrcA | RN70_06050 | RN70_06020 | 30S ribosomal protein S12 methylthiotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | HrcA family transcriptional regulator; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. | 0.630 |
| AKS73489.1 | lepA | RN70_06050 | RN70_06010 | 30S ribosomal protein S12 methylthiotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Elongation factor 4; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | 0.573 |
| AKS73489.1 | rpsT | RN70_06050 | RN70_06005 | 30S ribosomal protein S12 methylthiotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 30S ribosomal protein S20; Binds directly to 16S ribosomal RNA. | 0.410 |
| dnaK | AKS73489.1 | RN70_06030 | RN70_06050 | Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 30S ribosomal protein S12 methylthiotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.754 |
| dnaK | grpE | RN70_06030 | RN70_06025 | Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | Heat shock protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- [...] | 0.999 |
| dnaK | hemH | RN70_06030 | RN70_04950 | Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. | 0.662 |
| dnaK | hemN | RN70_06030 | RN70_06015 | Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | Coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | 0.638 |
| dnaK | hrcA | RN70_06030 | RN70_06020 | Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | HrcA family transcriptional regulator; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. | 0.984 |
| dnaK | lepA | RN70_06030 | RN70_06010 | Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | Elongation factor 4; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | 0.756 |
| dnaK | rpsT | RN70_06030 | RN70_06005 | Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 30S ribosomal protein S20; Binds directly to 16S ribosomal RNA. | 0.496 |
| gltB | hemE | RN70_11745 | RN70_04945 | Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.782 |
| gltB | hemN | RN70_11745 | RN70_06015 | Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | 0.632 |
| gltB | lepA | RN70_11745 | RN70_06010 | Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Elongation factor 4; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | 0.749 |
| gltB | rpsT | RN70_11745 | RN70_06005 | Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 30S ribosomal protein S20; Binds directly to 16S ribosomal RNA. | 0.470 |
| grpE | AKS73489.1 | RN70_06025 | RN70_06050 | Heat shock protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- [...] | 30S ribosomal protein S12 methylthiotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.701 |
| grpE | dnaK | RN70_06025 | RN70_06030 | Heat shock protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- [...] | Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.999 |
| grpE | hemN | RN70_06025 | RN70_06015 | Heat shock protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- [...] | Coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | 0.709 |
