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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
potDSpermidine/putrescine ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (357 aa)    
Predicted Functional Partners:
potC
Spermidine/purescine ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.999
potB
Spermidine/putrescine ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.998
potA
Spermidine/putrescine ABC transporter ATP-binding protein; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
 
 
 0.998
AKS73978.1
Cro/Cl family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.912
AKS73973.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.816
AKS73979.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0223 family.
       0.785
pdhC
Branched-chain alpha-keto acid dehydrogenase subunit E2; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.721
pdhD
Dihydrolipoamide dehydrogenase; E3 component of pyruvate complex; catalyzes the oxidation of dihydrolipoamide to lipoamide; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.714
AKS73261.1
Glutamate ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.473
pdhB
2-oxoisovalerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.447
Your Current Organism:
Staphylococcus schleiferi
NCBI taxonomy Id: 1295
Other names: ATCC 43808, CCUG 25351, CIP 103643, DSM 4807, LMG 13347, LMG:13347, NCTC 12218, NRRL B-14775, S. schleiferi, strain N850274
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