close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
graRResponse regulator GraR; Derived by automated computational analysis using gene prediction method: Protein Homology. (226 aa)    
Predicted Functional Partners:
graS
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 0.998
vraE
Bacitracin ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.953
AKS72517.1
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.930
AKS74344.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.907
hssS
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.841
saeS
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.810
AKS74345.1
Acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.791
vraF
Bacitracin ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.776
phoR
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.732
arlS
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.712
Your Current Organism:
Staphylococcus schleiferi
NCBI taxonomy Id: 1295
Other names: ATCC 43808, CCUG 25351, CIP 103643, DSM 4807, LMG 13347, LMG:13347, NCTC 12218, NRRL B-14775, S. schleiferi, strain N850274
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