close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AKS74389.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (432 aa)    
Predicted Functional Partners:
argS
arginine--tRNA ligase; Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.
      0.911
AKS74390.1
Acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.844
AKS74383.1
HAD family hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     0.807
AKS74388.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.754
AKS74387.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.707
AKS74382.1
Alpha/beta hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.660
AKS73469.1
GTPase; In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.631
AKS74391.1
NAD(P)H-dependent oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.526
rpoE
DNA-directed RNA polymerase subunit delta; Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling; Belongs to the RpoE family.
 
     0.506
AKS74256.1
Competence protein ComF; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.465
Your Current Organism:
Staphylococcus schleiferi
NCBI taxonomy Id: 1295
Other names: ATCC 43808, CCUG 25351, CIP 103643, DSM 4807, LMG 13347, LMG:13347, NCTC 12218, NRRL B-14775, S. schleiferi, strain N850274
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.