| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AKS73875.1 | codY | RN70_08175 | RN70_08030 | Negative regulator of genes involved in fatty acid and phospholipid biosynthesis for gram positive bacteria; Derived by automated computational analysis using gene prediction method: Protein Homology. | Transcriptional repressor CodY; DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor; Belongs to the CodY family. | 0.687 |
| AKS73875.1 | purR | RN70_08175 | RN70_11610 | Negative regulator of genes involved in fatty acid and phospholipid biosynthesis for gram positive bacteria; Derived by automated computational analysis using gene prediction method: Protein Homology. | Purine operon repressor; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.537 |
| AKS74487.1 | ipk | RN70_11605 | RN70_11615 | Endoribonuclease L-PSP; Derived by automated computational analysis using gene prediction method: Protein Homology. | 4-diphosphocytidyl-2C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol; Belongs to the GHMP kinase family. IspE subfamily. | 0.834 |
| AKS74487.1 | purR | RN70_11605 | RN70_11610 | Endoribonuclease L-PSP; Derived by automated computational analysis using gene prediction method: Protein Homology. | Purine operon repressor; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.877 |
| AKS74487.1 | spoVG | RN70_11605 | RN70_11600 | Endoribonuclease L-PSP; Derived by automated computational analysis using gene prediction method: Protein Homology. | Stage V sporulation protein G; Could be involved in septation. | 0.831 |
| codY | AKS73875.1 | RN70_08030 | RN70_08175 | Transcriptional repressor CodY; DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor; Belongs to the CodY family. | Negative regulator of genes involved in fatty acid and phospholipid biosynthesis for gram positive bacteria; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.687 |
| codY | purR | RN70_08030 | RN70_11610 | Transcriptional repressor CodY; DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor; Belongs to the CodY family. | Purine operon repressor; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.536 |
| gapR | purR | RN70_10150 | RN70_11610 | Central glycolytic genes regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | Purine operon repressor; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.515 |
| gapR | veg | RN70_10150 | RN70_11620 | Central glycolytic genes regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | Veg; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.642 |
| glmU | ipk | RN70_11595 | RN70_11615 | Glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. | 4-diphosphocytidyl-2C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol; Belongs to the GHMP kinase family. IspE subfamily. | 0.431 |
| glmU | prs | RN70_11595 | RN70_11590 | Glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. | 0.964 |
| glmU | purR | RN70_11595 | RN70_11610 | Glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. | Purine operon repressor; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.695 |
| glmU | spoVG | RN70_11595 | RN70_11600 | Glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. | Stage V sporulation protein G; Could be involved in septation. | 0.474 |
| guaA | prs | RN70_12025 | RN70_11590 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. | 0.821 |
| guaA | purR | RN70_12025 | RN70_11610 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Purine operon repressor; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.824 |
| ipk | AKS74487.1 | RN70_11615 | RN70_11605 | 4-diphosphocytidyl-2C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol; Belongs to the GHMP kinase family. IspE subfamily. | Endoribonuclease L-PSP; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.834 |
| ipk | glmU | RN70_11615 | RN70_11595 | 4-diphosphocytidyl-2C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol; Belongs to the GHMP kinase family. IspE subfamily. | Glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. | 0.431 |
| ipk | purR | RN70_11615 | RN70_11610 | 4-diphosphocytidyl-2C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol; Belongs to the GHMP kinase family. IspE subfamily. | Purine operon repressor; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.861 |
| ipk | spoVG | RN70_11615 | RN70_11600 | 4-diphosphocytidyl-2C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol; Belongs to the GHMP kinase family. IspE subfamily. | Stage V sporulation protein G; Could be involved in septation. | 0.599 |
| ipk | veg | RN70_11615 | RN70_11620 | 4-diphosphocytidyl-2C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol; Belongs to the GHMP kinase family. IspE subfamily. | Veg; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.578 |
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