node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ARB40441.1 | ribBA | B5728_06835 | B5728_06840 | Catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine; Derived by automated computational analysis using gene prediction method: Protein Homology. | Bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.999 |
ARB40441.1 | ribD | B5728_06835 | B5728_06830 | Catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine; Derived by automated computational analysis using gene prediction method: Protein Homology. | Pyridine nucleotide-disulfide oxidoreductase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.999 |
ARB41586.1 | folE2 | B5728_11355 | B5728_00485 | GTP pyrophosphokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | GTP cyclohydrolase I FolE2; Converts GTP to 7,8-dihydroneopterin triphosphate. | 0.800 |
ARB41586.1 | moaA | B5728_11355 | B5728_04575 | GTP pyrophosphokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | GTP 3',8-cyclase MoaA; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. | 0.800 |
ARB41586.1 | ndk | B5728_11355 | B5728_08470 | GTP pyrophosphokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.900 |
ARB41586.1 | pyk | B5728_11355 | B5728_07255 | GTP pyrophosphokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Pyruvate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the pyruvate kinase family. | 0.900 |
ARB41586.1 | ribBA | B5728_11355 | B5728_06840 | GTP pyrophosphokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.800 |
folE2 | ARB41586.1 | B5728_00485 | B5728_11355 | GTP cyclohydrolase I FolE2; Converts GTP to 7,8-dihydroneopterin triphosphate. | GTP pyrophosphokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.800 |
folE2 | moaA | B5728_00485 | B5728_04575 | GTP cyclohydrolase I FolE2; Converts GTP to 7,8-dihydroneopterin triphosphate. | GTP 3',8-cyclase MoaA; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. | 0.900 |
folE2 | ndk | B5728_00485 | B5728_08470 | GTP cyclohydrolase I FolE2; Converts GTP to 7,8-dihydroneopterin triphosphate. | Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.800 |
folE2 | pyk | B5728_00485 | B5728_07255 | GTP cyclohydrolase I FolE2; Converts GTP to 7,8-dihydroneopterin triphosphate. | Pyruvate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the pyruvate kinase family. | 0.810 |
folE2 | ribBA | B5728_00485 | B5728_06840 | GTP cyclohydrolase I FolE2; Converts GTP to 7,8-dihydroneopterin triphosphate. | Bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.909 |
guaB | ndk | B5728_01270 | B5728_08470 | GMP synthase (glutamine-hydrolyzing); Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.508 |
guaB | pyk | B5728_01270 | B5728_07255 | GMP synthase (glutamine-hydrolyzing); Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Pyruvate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the pyruvate kinase family. | 0.711 |
guaB | ribBA | B5728_01270 | B5728_06840 | GMP synthase (glutamine-hydrolyzing); Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.926 |
guaB | ribD | B5728_01270 | B5728_06830 | GMP synthase (glutamine-hydrolyzing); Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Pyridine nucleotide-disulfide oxidoreductase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.841 |
guaB | rsmB | B5728_01270 | B5728_10140 | GMP synthase (glutamine-hydrolyzing); Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 16S rRNA (cytosine(967)-C(5))-methyltransferase; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | 0.422 |
guaB | secD | B5728_01270 | B5728_07525 | GMP synthase (glutamine-hydrolyzing); Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Protein translocase subunit SecDF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA; Belongs to the SecD/SecF family. SecD subfamily. | 0.518 |
moaA | ARB41586.1 | B5728_04575 | B5728_11355 | GTP 3',8-cyclase MoaA; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. | GTP pyrophosphokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.800 |
moaA | folE2 | B5728_04575 | B5728_00485 | GTP 3',8-cyclase MoaA; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. | GTP cyclohydrolase I FolE2; Converts GTP to 7,8-dihydroneopterin triphosphate. | 0.900 |