| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ARB40733.1 | ARB40736.1 | B5728_08670 | B5728_08685 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0403 family. | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | 0.748 |
| ARB40733.1 | ARB40738.1 | B5728_08670 | B5728_08695 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0403 family. | Fatty acid-binding protein DegV; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.755 |
| ARB40733.1 | ARB40742.1 | B5728_08670 | B5728_08715 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0403 family. | PTS glucose transporter subunit IIA; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.676 |
| ARB40733.1 | ARB40743.1 | B5728_08670 | B5728_08720 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0403 family. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0346 family. | 0.676 |
| ARB40733.1 | msrA-2 | B5728_08670 | B5728_08705 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0403 family. | Peptide-methionine (S)-S-oxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. | 0.718 |
| ARB40733.1 | msrB | B5728_08670 | B5728_08710 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0403 family. | Peptide-methionine (R)-S-oxide reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.718 |
| ARB40733.1 | thyA | B5728_08670 | B5728_08680 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0403 family. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.756 |
| ARB40736.1 | ARB40733.1 | B5728_08685 | B5728_08670 | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0403 family. | 0.748 |
| ARB40736.1 | ARB40737.1 | B5728_08685 | B5728_08690 | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | 1-acyl-sn-glycerol-3-phosphate acyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. | 0.849 |
| ARB40736.1 | ARB40738.1 | B5728_08685 | B5728_08695 | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | Fatty acid-binding protein DegV; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.881 |
| ARB40736.1 | ARB40742.1 | B5728_08685 | B5728_08715 | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | PTS glucose transporter subunit IIA; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.855 |
| ARB40736.1 | ARB40743.1 | B5728_08685 | B5728_08720 | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0346 family. | 0.851 |
| ARB40736.1 | msrA-2 | B5728_08685 | B5728_08705 | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | Peptide-methionine (S)-S-oxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. | 0.869 |
| ARB40736.1 | msrB | B5728_08685 | B5728_08710 | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | Peptide-methionine (R)-S-oxide reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.869 |
| ARB40736.1 | thyA | B5728_08685 | B5728_08680 | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.999 |
| ARB40737.1 | ARB40736.1 | B5728_08690 | B5728_08685 | 1-acyl-sn-glycerol-3-phosphate acyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | 0.849 |
| ARB40737.1 | ARB40738.1 | B5728_08690 | B5728_08695 | 1-acyl-sn-glycerol-3-phosphate acyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. | Fatty acid-binding protein DegV; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.806 |
| ARB40737.1 | ARB40742.1 | B5728_08690 | B5728_08715 | 1-acyl-sn-glycerol-3-phosphate acyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. | PTS glucose transporter subunit IIA; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.689 |
| ARB40737.1 | ARB40743.1 | B5728_08690 | B5728_08720 | 1-acyl-sn-glycerol-3-phosphate acyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0346 family. | 0.689 |
| ARB40737.1 | msrA-2 | B5728_08690 | B5728_08705 | 1-acyl-sn-glycerol-3-phosphate acyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. | Peptide-methionine (S)-S-oxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. | 0.717 |