STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ARB40878.12-oxoacid ferredoxin oxidoreductase; Catalyzes the coenzyme A dependent formation of succinyl-CoA from 2-oxoglutarate and ferredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. (288 aa)    
Predicted Functional Partners:
ARB40879.1
2-oxoglutarate ferredoxin oxidoreductase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.999
pyk
Pyruvate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the pyruvate kinase family.
  
 0.938
ldh
L-lactate permease; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family.
  
 
 0.931
sucD
succinate--CoA ligase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
  
 
 0.926
pta
Phosphate acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.923
ilvB
Acetolactate synthase, large subunit, biosynthetic type; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.919
ARB40508.1
Citrate synthase; Catalyzes the formation of citrate from acetyl-CoA and oxaloacetate; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.919
leuA
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
  
 
 0.916
ARB39806.1
acyl--CoA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.914
acsA
acetate--CoA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.914
Your Current Organism:
Staphylococcus sciuri
NCBI taxonomy Id: 1296
Other names: ATCC 29062, BCRC 12927, CCM 3473, CCUG 15598, CIP 81.62, CNCTC 5683, DSM 20345, JCM 2425, NCTC 12103, NRRL B-14777, S. sciuri, SC 116, strain DD 4277
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