STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SFU00357.18-oxo-dGTP diphosphatase. (249 aa)    
Predicted Functional Partners:
nnrE
yjeF C-terminal region, hydroxyethylthiazole kinase-related/yjeF N-terminal region; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specif [...]
  
 0.951
SFU09407.1
Exoribonuclease R.
   
 0.773
SFT91438.1
Anti-anti-sigma factor.
    
 0.750
ribBA
3,4-dihydroxy 2-butanone 4-phosphate synthase / GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
   
  0.740
SFT82360.1
GTP cyclohydrolase II /3,4-dihydroxy-2-butanone 4-phosphate synthase; In the N-terminal section; belongs to the DHBP synthase family.
   
  0.740
rph
Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
 
  
 0.700
nadE
NAD+ synthase (glutamine-hydrolysing); Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
   
 0.699
SFU09723.1
Competence/damage-inducible protein cinA; Belongs to the CinA family.
    
 0.677
SFU08608.1
Hypothetical protein.
  
 0.637
SFT55752.1
Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
    
  0.629
Your Current Organism:
Geodermatophilus amargosae
NCBI taxonomy Id: 1296565
Other names: ATCC 25081, CCUG 62971, DSM 46136, G. amargosae, Geodermatophilus amargosae Montero-Calasanz et al. 2014, Geodermatophilus obscurus subsp. amargosae, Geodermatophilus sp. DSM 46136, JCM 3153, KCTC 9360, MTCC 11559, NBRC 13316, NRRL B-3578, strain G12
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