STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ALP92408.1Quinolone resistance protein. (217 aa)    
Predicted Functional Partners:
gyrB
DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
   
 
 0.629
ALP93106.1
Hypothetical protein; FIG01232333.
   
 
 0.629
ALP93467.1
DNA gyrase subunit B.
   
 
 0.629
ALP93836.1
Hypothetical protein.
 
 
 
 0.606
ALP92404.1
Hypothetical protein.
  
 
 0.591
ALP93086.1
Hypothetical protein.
   
 
 0.559
ALP92409.1
Lipoteichoic acid synthase LtaS Type IIb.
  
    0.552
ALP92407.1
Transporter.
       0.548
ALP94023.1
LysM domain-containing membrane protein.
   
 
 0.532
ALP92757.1
Transport protein.
  
     0.464
Your Current Organism:
Intestinimonas butyriciproducens
NCBI taxonomy Id: 1297617
Other names: CCUG 63529, Candidatus Clostridium anorexicus, DSM 26588, I. butyriciproducens, Intestinimonas butyriciproducens Klaring et al. 2013, Pseudoflavonifractor sp. 2-1.1, Pseudoflavonifractor sp. SRB-521-5-I, strain SRB-521-5-I
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.